Parasympathetic nervous system dysfunction in primary Sjögren's syndrome.
نویسندگان
چکیده
In the past sicca syndromes were attributed to destruction of glandular tissue. It is now thought that cytokines, autoantibodies, and parasympathetic nervous system dysfunction all have an important role in the xerostomia and xerophthalmia in Sjögren's syndrome.
منابع مشابه
Parasympathetic failure does not contribute to ocular dryness in primary Sjögren's syndrome.
OBJECTIVE To investigate the sympathetic and parasympathetic cardiovascular function in primary Sjögren's syndrome (SS) and to investigate the possible relation with ocular dryness. METHODS 41 (40 women) patients with primary SS, mean age 50 years (range 20-80) with a mean disease duration of eight years (range 1-30), were studied. In each patient direct arterial blood pressure (BP), heart ra...
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BACKGROUND Sjögren's syndrome can involve the central nervous system; however, spontaneous intracranial hemorrhage has rarely been reported as the initial manifestation. CASE PRESENTATION We report a 39-year-old woman with primary Sjögren's syndrome presenting with intracranial hemorrhage. The diagnosis of primary Sjögren's syndrome was based on the presence of ocular dryness, salivary gland ...
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Primary Sjögren's syndrome, a chronic inflammatory process, is among the most commonly occurring rheumatologic diseases. The clinical hallmark of this disease is exocrine gland dysfunction, resulting predominately in dry eyes and dry mouth. However, the disease often extends beyond the exocrine glands to seriously affect other organs systems, such as the lungs, kidneys, and nervous system. More...
متن کاملAutonomic nervous symptoms in primary Sjogren's syndrome.
OBJECTIVES Objective signs of autonomic dysfunction (AD) have been reported in patients with primary SS (pSS) while the presence of associated symptoms has not been systematically studied. Therefore, the aims of this study were (i) to assess the presence and severity of various AD symptoms in pSS patients and (ii) to relate AD symptoms to other clinical features of pSS. METHODS Thirty-eight p...
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BACKGROUND/AIMS To determine the prevalence of autonomic dysfunction among Korean patients with primary Sjogren's syndrome (pSS) and its associations with the clinical features of pSS. METHODS We analyzed 154 participants from the Korean Initiative of primary Sjogren's Syndrome (KISS) as a prospective pSS cohort and 154 age- and sex-matched healthy controls. A standardized 5-minute, supine, r...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 62 8 شماره
صفحات -
تاریخ انتشار 2003